Yes! Neuromodulators such as Botox have been used for cosmetic purposes for over 20 years and have proven to be very safe through extensive testing and research. Rarely, there can be some minor bruising which is not permanent (and is easily covered up with makeup) or a slight short-term headache. A temporary eyelid droop is also possible for very rare. While not without potential side effects but there has not been a confirmed serious case of spread of toxin effect away from the injection site when BOTOX® Cosmetic has been used at the recommended dose to treat frown lines.